Animal Care and Use (IACUC)
Animal Care and Use (IACUC)
Oklahoma State University is committed to providing an animal care and use program that provides a humane and compliant environment for all animals involved in research, teaching, and testing activities. Every effort is made to adhere to all federal, state, and local laws and regulations that govern the care and use of animals. All research, teaching and testing activities involving live, vertebrate animals must be approved by the Institutional Animal Care and Use Committee (IACUC). Information provided on this site is designed to help you gain that approval.
Start my IACUC application
- What is the Institutional Animal Care and Use Committee?
All research, teaching, and testing activities involving live, vertebrate animals must be approved by the Institutional Animal Care and Use Committee (IACUC). The IACUC is responsible for overseeing campus animal care and use programs; monitoring the care, use, and treatment of animals; ensuring compliance with applicable laws, regulations standards; and University policies pertaining to the care and use of animals.
The committee is guided by:
Institutional policy: Care and Use of Animals in Research, Testing, and Teaching policy
IACUC policy and procedures: OSU CHS Animal Care and Use Handbook
- What needs IACUC approval?
Any living, non-human, vertebrate animal (i.e., amphibians, birds, fish, mammals, and reptiles) used or intended for use in research, research training, teaching, and testing. This does not include campus therapy pets (e.g. OSU Pete’s Pet Posse).
- How do I get started?
Submit an application to
Note: Researchers should use their OSU SSO Credentials to login. After login, the user should be able to navigate between the IACUC and IBC modules within the system.
We have created some guidance on using the IACUC module within Cayuse
Note: The links will require login to Sharepoint
- IACUC Researcher Training - Getting Started
- IACUC Researcher Animal Inventory
- IACUC Researcher Animal Procurement
IACUC Member (Reviewer) Guidance
For additional tutorials and tips, you can go to Cayuse's Help Center at https://support.cayuse.com
- I have heard about “Experimental Design Assistant.” How does that work?
Experimental Design Assistant is a free online tool from the NC3Rs, designed to guide researchers through the design of their experiments, helping to ensure that they use the minimum number of animals consistent with their scientific objectives, methods to reduce subjective bias, and appropriate statistical analysis.
The EDA website also provides information about the different concepts of experimental design, and how to apply these in your experiments.
Once you draft a design via EDA, it can be easily inserted into your IACUC (Cayuse) application. This format aids the IACUC in understanding your research design. Additionally, the design can be inserted into grant proposals.
- When does IACUC meet?
The committee meets bi-monthly (February, April, June, Aug, October, December). Please plan accordingly.
- What training is required?
Animal welfare regulations and Public Health Service policy require institutions to ensure that people caring for or using animals are qualified to do so. Oklahoma State University Center for Health Sciences (OSU CHS) is charged with providing training opportunities to meet these regulations. Consequently, all personnel (e.g., principal investigators/instructors (PIs), research faculty/staff, graduate students, laboratory technicians, students, etc.) involved in animal care and/or use of live vertebrate animals in research, teaching, or testing at OSU CHS must complete prescribed mandatory training prior to protocol approval and prior to working with animals.
OSU CHS offers initial orientation training and an online web-based training course provided through the CITI. If you would like to request training on a specific topic not covered in CITI or set up an in-person IACUC training, please contact the firstname.lastname@example.org.
Other training resources (optional):
- What is our Animal Welfare Assurance (Assurance)?
The Assurance is the principal document between OSU CHS and the Public Health Service’s Office of Laboratory Animal Welfare (OLAW) defining the relationship between the entities in terms of the campus’ animal care and use program. The campus Institutional Official signs the Assurance, which commits the campus to adherence to the PHS policy. An Assurance may be renewed every four years.
Our Animal Welfare Assurance: A3679-01
How do I report an animal welfare concern?
It is the policy of OSU-CHS that the care, use and treatment of university-owned laboratory animals should be of high quality and in compliance with all federal, state, and local regulations. Any person with knowledge of deficiencies or with reasonable suspicions of deficiencies or mistreatment involving OSU-CHS laboratory animals is obligated to report them directly to a member of the IACUC or research compliance, Individuals may also file their concerns through Ethics Point. Reports to Ethics Point can be made online or toll-free at 866-294-8692. Timely reporting is essential to protect the animals involved and to aid the investigation of the allegations.
- Where can I find additional guidance?
There are various sources of information you can consult with regard to working with animals in research, teaching, and testing activities. One very good source is the Guide for the Care and Use of Laboratory Animals, more commonly referred to as the Guide. The purpose of the Guide is to assist institutions in caring for and using animals in ways judged to be scientifically, technically, and humanely appropriate. The Guide is also intended to assist investigators in fulfilling their obligation to plan and conduct animal activities in accord with the highest scientific, humane, and ethical principles.
The Office of Laboratory Animal Welfare (OLAW) has created a brochure intended to communicate responsibilities to principle investigators. "What Investigators Need to Know About the Use of Animals" is a succinct resource that allows individuals to quickly grasp the main expectations and requirements of animal care and use.
Numerous laws, policies, and regulations govern the use of animals in research, teaching, and testing. The federal government has provided guidance in many areas.
The IACUC application is asking about a literature search of alternatives. Where do
I find more information?
According to the Institutional Animal Care and Use Committee Guidebook, there is increasing public interest in exploring alternatives to the use of animals in research and testing. IACUCs regularly consider the question, "Is there an alternative to using live animals in this proposal?" Some suggest that the only acceptable alternatives are those that completely replace animals, while others have less restrictive definitions. The definition of alternatives that allows a degree of common understanding was developed by Russell and Burch, and is referred to as the three "Rs"- replacement, refinement, and reduction.
Tell me more about the Post-Approval Monitoring Program.
The role of Post-Approval Monitor has been developed to provide assurance to regulatory agencies and Oklahoma State University Center for Health Sciences that research and academic programs using live vertebrate animals are monitored for compliance with federal regulations, approved ACUPs and Standard Operating Procedures at OSU CHS sites and facilities. This program is designed to assist those individuals involved with research, testing and/or teaching at OSU CHS. The goal is to facilitate a better understanding of the regulatory standards associated with the advancement of scientific and academic excellence at OSU CHS>